Chemotherapeutic agents against pathogenic animal trypanosomes
نویسندگان
چکیده
Trypanosomoses are protozoan diseases, affecting both human and animals, and mainly found in tropical Africa, Latin America and Asia. In Africa, trypanosomes produce serious diseases in human beings such as West and East Sleeping Sickness caused by T. brucei gambiense and T. brucei congolense respectively, while in the Americas T. cruzi causes the Chagas disease. Other species of Trypanosoma affect animals and produce enormous economical impact in the endemic areas. Those species could be classified as those transmitted by tsetse flies(Trypanosoma vivax, T. congolense and T. brucei brucei) producing a disease known as nagana and those non-transmitted by tsetse(T. evansi –surra-, T. equiperdum –dourine-).
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